STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1494 aa)    
Predicted Functional Partners:
VWF
Von Willebrand factor.
    
 0.915
DGKE
Diacylglycerol kinase.
      
 0.880
THBD
Thrombomodulin.
    
 0.861
MMACHC
Metabolism of cobalamin associated C.
      
 0.792
C2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
  
 0.766
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
      
 0.661
POFUT2
Protein O-fucosyltransferase 2.
     
 0.654
W5PX64_SHEEP
Uncharacterized protein.
     
 0.642
W5PWS0_SHEEP
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
     
 0.634
LOC105611355
Uncharacterized protein.
     
 0.634
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.