STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMIM17Small integral membrane protein 17. (115 aa)    
Predicted Functional Partners:
TMEM214
Transmembrane protein 214.
      
 0.679
TMEM68
Transmembrane protein 68.
      
 0.634
AMZ2
Archaelysin family metallopeptidase 2.
      
 0.613
PHACTR3
Phosphatase and actin regulator.
      
 0.613
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
      
 0.586
NDUFA3
NADH:ubiquinone oxidoreductase subunit A3.
      
 0.556
W5PYS4_SHEEP
PH domain-containing protein.
      
 0.535
CGNL1
Cingulin like 1.
      
 0.535
OPALIN
Oligodendrocytic myelin paranodal and inner loop protein.
      
 0.529
TPM3
Tropomyosin 3; Belongs to the tropomyosin family.
      
 0.483
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.