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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNK1Potassium two pore domain channel subfamily K member 1. (219 aa)    
Predicted Functional Partners:
KCNK18
Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.845
KCNK9
Uncharacterized protein.
   
 
 0.765
KCNK2
Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.713
KCNK10
Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.699
KCNK12
Potassium two pore domain channel subfamily K member 12.
   
 
0.694
KCNK17
Potassium two pore domain channel subfamily K member 17.
     
0.685
KCNK15
Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.650
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.614
SYT16
Synaptotagmin 16.
      
 0.604
KCNQ2
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
      
 0.592
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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