STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAMP2Receptor activity modifying protein 2. (177 aa)    
Predicted Functional Partners:
ADM
Adrenomedullin.
    
 0.999
CALCRL
Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.999
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.993
CALCA
Calcitonin; Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones; Belongs to the calcitonin family.
    
 0.975
RAMP1
Uncharacterized protein.
     
0.964
IAPP
Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family.
    
 0.938
W5P8F8_SHEEP
CALCITONIN domain-containing protein.
     
 0.928
RAMP3
Receptor activity modifying protein 3.
   
 
0.712
CRSP1
Calcitonin receptor-stimulating peptide 1; Stimulates cAMP production via the calcitonin receptor (CT) but not via the CT-like (CL) receptor.
    
 0.701
VIPR2
Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family.
    
 0.673
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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