STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AURKCProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)    
Predicted Functional Partners:
INCENP
Inner centromere protein.
   
 0.959
CDCA8
Cell division cycle associated 8.
   
 0.946
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.890
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.831
CDK1
Cell division cycle 2 protein isoform 1; Belongs to the protein kinase superfamily.
  
0.830
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.809
UBE2C
Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.800
W5P3V9_SHEEP
Protein kinase domain-containing protein.
   
 0.797
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.794
BUB1B
Uncharacterized protein.
   
 0.787
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.