W5P028_SHEEP protein (Ovis aries) - STRING interaction network

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Score

W5P028_SHEEP

Uncharacterized protein. (171 aa)

Predicted Functional Partners:

ADSL

0.728

TNFAIP8L1

0.701

RRM1

0.693

GART

0.692

PPP1R14C

0.678

ATP5PO

0.665

ATP6

0.640

MTAP

0.621

W5NRS0_SHEEP

0.616

GAPDHS

0.598

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSL	GART	ENSOARP00000018572	ENSOARP00000014076	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.999
ADSL	RRM1	ENSOARP00000018572	ENSOARP00000001360	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.545
ADSL	W5NRS0_SHEEP	ENSOARP00000018572	ENSOARP00000000860	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	PNP_UDP_1 domain-containing protein.	0.425
ADSL	W5P028_SHEEP	ENSOARP00000018572	ENSOARP00000003776	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	Uncharacterized protein.	0.728
ATP5PO	ATP6	ENSOARP00000013679	ENSOARP00000000006	Uncharacterized protein.	ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]	0.999
ATP5PO	W5P028_SHEEP	ENSOARP00000013679	ENSOARP00000003776	Uncharacterized protein.	Uncharacterized protein.	0.665
ATP6	ATP5PO	ENSOARP00000000006	ENSOARP00000013679	ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]	Uncharacterized protein.	0.999
ATP6	W5P028_SHEEP	ENSOARP00000000006	ENSOARP00000003776	ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]	Uncharacterized protein.	0.640
GAPDHS	GART	ENSOARP00000005200	ENSOARP00000014076	Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.422
GAPDHS	W5P028_SHEEP	ENSOARP00000005200	ENSOARP00000003776	Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Uncharacterized protein.	0.598
GART	ADSL	ENSOARP00000014076	ENSOARP00000018572	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.999
GART	GAPDHS	ENSOARP00000014076	ENSOARP00000005200	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.422
GART	MTAP	ENSOARP00000014076	ENSOARP00000015465	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.506
GART	RRM1	ENSOARP00000014076	ENSOARP00000001360	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.689
GART	W5NRS0_SHEEP	ENSOARP00000014076	ENSOARP00000000860	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	PNP_UDP_1 domain-containing protein.	0.499
GART	W5P028_SHEEP	ENSOARP00000014076	ENSOARP00000003776	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Uncharacterized protein.	0.692
MTAP	GART	ENSOARP00000015465	ENSOARP00000014076	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.506
MTAP	W5NRS0_SHEEP	ENSOARP00000015465	ENSOARP00000000860	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	PNP_UDP_1 domain-containing protein.	0.442
MTAP	W5P028_SHEEP	ENSOARP00000015465	ENSOARP00000003776	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Uncharacterized protein.	0.621
PPP1R14C	TNFAIP8L1	ENSOARP00000003134	ENSOARP00000017767	Uncharacterized protein.	TNF alpha induced protein 8 like 1.	0.708