WNK4 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

WNK4

WNK lysine deficient protein kinase 4. (1139 aa)

Predicted Functional Partners:

KLHL3

0.957

KLHL2

0.899

CUL3

0.887

SLC12A3

0.882

OXSR1

0.777

KCNH4

0.717

SCNN1B

0.685

JUN

0.658

JUNB

0.658

BSND

0.654

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BSND	OXSR1	ENSOARP00000008078	ENSOARP00000001135	Barttin CLCNK type accessory beta subunit.	Oxidative stress responsive kinase 1.	0.649
BSND	SCNN1B	ENSOARP00000008078	ENSOARP00000018011	Barttin CLCNK type accessory beta subunit.	Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...]	0.476
BSND	SLC12A3	ENSOARP00000008078	ENSOARP00000020138	Barttin CLCNK type accessory beta subunit.	Solute carrier family 12 member 3.	0.551
BSND	WNK4	ENSOARP00000008078	ENSOARP00000003828	Barttin CLCNK type accessory beta subunit.	WNK lysine deficient protein kinase 4.	0.654
CUL3	KLHL2	ENSOARP00000021930	ENSOARP00000017185	Cullin 3; Belongs to the cullin family.	Kelch like family member 2.	0.955
CUL3	KLHL3	ENSOARP00000021930	ENSOARP00000016491	Cullin 3; Belongs to the cullin family.	Kelch like family member 3.	0.996
CUL3	SCNN1B	ENSOARP00000021930	ENSOARP00000018011	Cullin 3; Belongs to the cullin family.	Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...]	0.476
CUL3	WNK4	ENSOARP00000021930	ENSOARP00000003828	Cullin 3; Belongs to the cullin family.	WNK lysine deficient protein kinase 4.	0.887
JUN	WNK4	ENSOARP00000010722	ENSOARP00000003828	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	WNK lysine deficient protein kinase 4.	0.658
JUNB	WNK4	ENSOARP00000011637	ENSOARP00000003828	JunB proto-oncogene, AP-1 transcription factor subunit.	WNK lysine deficient protein kinase 4.	0.658
KCNH4	WNK4	ENSOARP00000020184	ENSOARP00000003828	Potassium voltage-gated channel subfamily H member 4.	WNK lysine deficient protein kinase 4.	0.717
KLHL2	CUL3	ENSOARP00000017185	ENSOARP00000021930	Kelch like family member 2.	Cullin 3; Belongs to the cullin family.	0.955
KLHL2	KLHL3	ENSOARP00000017185	ENSOARP00000016491	Kelch like family member 2.	Kelch like family member 3.	0.715
KLHL2	SLC12A3	ENSOARP00000017185	ENSOARP00000020138	Kelch like family member 2.	Solute carrier family 12 member 3.	0.762
KLHL2	WNK4	ENSOARP00000017185	ENSOARP00000003828	Kelch like family member 2.	WNK lysine deficient protein kinase 4.	0.899
KLHL3	CUL3	ENSOARP00000016491	ENSOARP00000021930	Kelch like family member 3.	Cullin 3; Belongs to the cullin family.	0.996
KLHL3	KLHL2	ENSOARP00000016491	ENSOARP00000017185	Kelch like family member 3.	Kelch like family member 2.	0.715
KLHL3	OXSR1	ENSOARP00000016491	ENSOARP00000001135	Kelch like family member 3.	Oxidative stress responsive kinase 1.	0.409
KLHL3	SCNN1B	ENSOARP00000016491	ENSOARP00000018011	Kelch like family member 3.	Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...]	0.573
KLHL3	SLC12A3	ENSOARP00000016491	ENSOARP00000020138	Kelch like family member 3.	Solute carrier family 12 member 3.	0.694