| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP2B1 | CALM3 | ENSOARP00000006806 | ENSOARP00000011414 | AP complex subunit beta. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.482 |
| AP2B1 | NFAT5 | ENSOARP00000006806 | ENSOARP00000003834 | AP complex subunit beta. | Nuclear factor of activated T cells 5. | 0.684 |
| AP2B1 | REN | ENSOARP00000006806 | ENSOARP00000002426 | AP complex subunit beta. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.562 |
| CALM3 | AP2B1 | ENSOARP00000011414 | ENSOARP00000006806 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | AP complex subunit beta. | 0.482 |
| CALM3 | CREB1 | ENSOARP00000011414 | ENSOARP00000020245 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | cAMP responsive element binding protein 1. | 0.680 |
| CALM3 | NFAT5 | ENSOARP00000011414 | ENSOARP00000003834 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Nuclear factor of activated T cells 5. | 0.512 |
| CALM3 | REN | ENSOARP00000011414 | ENSOARP00000002426 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.490 |
| CREB1 | CALM3 | ENSOARP00000020245 | ENSOARP00000011414 | cAMP responsive element binding protein 1. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 0.680 |
| CREB1 | EGR1 | ENSOARP00000020245 | ENSOARP00000017688 | cAMP responsive element binding protein 1. | DUF3446 domain-containing protein. | 0.723 |
| CREB1 | FOS | ENSOARP00000020245 | ENSOARP00000001873 | cAMP responsive element binding protein 1. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.699 |
| CREB1 | FOSB | ENSOARP00000020245 | ENSOARP00000010701 | cAMP responsive element binding protein 1. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.654 |
| CREB1 | NFAT5 | ENSOARP00000020245 | ENSOARP00000003834 | cAMP responsive element binding protein 1. | Nuclear factor of activated T cells 5. | 0.656 |
| CREB1 | OPA3 | ENSOARP00000020245 | ENSOARP00000010844 | cAMP responsive element binding protein 1. | Uncharacterized protein. | 0.409 |
| EGR1 | CREB1 | ENSOARP00000017688 | ENSOARP00000020245 | DUF3446 domain-containing protein. | cAMP responsive element binding protein 1. | 0.723 |
| EGR1 | FOS | ENSOARP00000017688 | ENSOARP00000001873 | DUF3446 domain-containing protein. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.956 |
| EGR1 | FOSB | ENSOARP00000017688 | ENSOARP00000010701 | DUF3446 domain-containing protein. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.919 |
| EGR1 | NFAT5 | ENSOARP00000017688 | ENSOARP00000003834 | DUF3446 domain-containing protein. | Nuclear factor of activated T cells 5. | 0.539 |
| FOS | CREB1 | ENSOARP00000001873 | ENSOARP00000020245 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | cAMP responsive element binding protein 1. | 0.699 |
| FOS | EGR1 | ENSOARP00000001873 | ENSOARP00000017688 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | DUF3446 domain-containing protein. | 0.956 |
| FOS | FOSB | ENSOARP00000001873 | ENSOARP00000010701 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.943 |
STRING v12.5 is now available!
