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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NID1Nidogen 1. (1242 aa)    
Predicted Functional Partners:
HSPG2
Heparan sulfate proteoglycan 2.
   
 0.912
LAMC1
Laminin subunit gamma 1.
   
 0.911
MMP19
Matrix metallopeptidase 19.
     
 0.839
LAMA4
Laminin subunit alpha 4.
   
 0.783
AGRN
Uncharacterized protein.
   
 0.723
LAMB1
Laminin subunit beta 1.
   
 0.706
LAMC3
Laminin subunit gamma 3.
   
 0.693
COL5A2
Collagen type V alpha 2 chain.
   
 0.683
LAMA2
Laminin subunit alpha 2.
   
 0.673
W5NVE0_SHEEP
Uncharacterized protein.
   
 0.666
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.