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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTDSPL2CTD small phosphatase like 2. (466 aa)    
Predicted Functional Partners:
GTF2F1
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.748
KLHDC1
Kelch domain containing 1.
   
 
 0.722
GAS2L1
Growth arrest specific 2 like 1.
    
 
 0.710
LOC101118849
Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
    
 0.645
POLR2G
S1 domain-containing protein.
    
 0.599
POLR2D
RNA polymerase II subunit D.
    
 0.595
TIMM21
Translocase of inner mitochondrial membrane 21.
    
 0.589
AGGF1
Uncharacterized protein.
      
 0.587
PDIK1L
PDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily.
   
 
 0.579
LPIN3
Lipin 3.
    
 0.550
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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