LGALS8 protein (Ovis aries) - STRING interaction network

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[Homology]

Score

LGALS8

Galectin. (338 aa)

Predicted Functional Partners:

CALCOCO2

0.848

TAX1BP1

0.785

LGALS15

0.699

WIPF3

0.631

LGALS1

0.604

ITGA3

0.573

BRCA1

0.552

ARMH3

0.550

MUC13

0.522

ITGA4

0.517

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMH3	LGALS8	ENSOARP00000018436	ENSOARP00000003873	Armadillo like helical domain containing 3.	Galectin.	0.550
ARMH3	WIPF3	ENSOARP00000018436	ENSOARP00000009448	Armadillo like helical domain containing 3.	WAS/WASL interacting protein family member 3.	0.808
BRCA1	LGALS8	ENSOARP00000005185	ENSOARP00000003873	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Galectin.	0.552
CALCOCO2	LGALS8	ENSOARP00000007179	ENSOARP00000003873	Calcium binding and coiled-coil domain 2.	Galectin.	0.848
CALCOCO2	TAX1BP1	ENSOARP00000007179	ENSOARP00000009855	Calcium binding and coiled-coil domain 2.	Tax1 binding protein 1.	0.965
ITGA3	ITGA4	ENSOARP00000005814	ENSOARP00000018121	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.815
ITGA3	LGALS8	ENSOARP00000005814	ENSOARP00000003873	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Galectin.	0.573
ITGA4	ITGA3	ENSOARP00000018121	ENSOARP00000005814	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.815
ITGA4	LGALS8	ENSOARP00000018121	ENSOARP00000003873	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Galectin.	0.517
LGALS1	LGALS15	ENSOARP00000014976	ENSOARP00000020500	Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis.	Galectin.	0.683
LGALS1	LGALS8	ENSOARP00000014976	ENSOARP00000003873	Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis.	Galectin.	0.604
LGALS1	MUC13	ENSOARP00000014976	ENSOARP00000021719	Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis.	Uncharacterized protein.	0.418
LGALS15	LGALS1	ENSOARP00000020500	ENSOARP00000014976	Galectin.	Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis.	0.683
LGALS15	LGALS8	ENSOARP00000020500	ENSOARP00000003873	Galectin.	Galectin.	0.699
LGALS8	ARMH3	ENSOARP00000003873	ENSOARP00000018436	Galectin.	Armadillo like helical domain containing 3.	0.550
LGALS8	BRCA1	ENSOARP00000003873	ENSOARP00000005185	Galectin.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.552
LGALS8	CALCOCO2	ENSOARP00000003873	ENSOARP00000007179	Galectin.	Calcium binding and coiled-coil domain 2.	0.848
LGALS8	ITGA3	ENSOARP00000003873	ENSOARP00000005814	Galectin.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.573
LGALS8	ITGA4	ENSOARP00000003873	ENSOARP00000018121	Galectin.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.517
LGALS8	LGALS1	ENSOARP00000003873	ENSOARP00000014976	Galectin.	Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis.	0.604