W5P0G0_SHEEP protein (Ovis aries) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

W5P0G0_SHEEP

Uncharacterized protein. (97 aa)

Predicted Functional Partners:

INSR

0.996

IDE

0.982

IGF1R

0.966

GHRL

0.947

INSRR

0.866

P4HB

0.866

SST

0.858

ALB

0.853

SLC2A4

0.837

PAX4

0.824

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	GHRL	ENSOARP00000014782	ENSOARP00000012362	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Uncharacterized protein.	0.527
ALB	IGF1R	ENSOARP00000014782	ENSOARP00000010738	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Tyrosine-protein kinase receptor.	0.581
ALB	SLC2A4	ENSOARP00000014782	ENSOARP00000012275	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.581
ALB	SST	ENSOARP00000014782	ENSOARP00000022014	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.	0.686
ALB	W5P0G0_SHEEP	ENSOARP00000014782	ENSOARP00000003908	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Uncharacterized protein.	0.853
GHRL	ALB	ENSOARP00000012362	ENSOARP00000014782	Uncharacterized protein.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.527
GHRL	PAX4	ENSOARP00000012362	ENSOARP00000002050	Uncharacterized protein.	Paired box 4.	0.614
GHRL	SST	ENSOARP00000012362	ENSOARP00000022014	Uncharacterized protein.	Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.	0.863
GHRL	W5P0G0_SHEEP	ENSOARP00000012362	ENSOARP00000003908	Uncharacterized protein.	Uncharacterized protein.	0.947
IDE	W5P0G0_SHEEP	ENSOARP00000000325	ENSOARP00000003908	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.982
IGF1R	ALB	ENSOARP00000010738	ENSOARP00000014782	Tyrosine-protein kinase receptor.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.581
IGF1R	INSR	ENSOARP00000010738	ENSOARP00000000278	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.861
IGF1R	INSRR	ENSOARP00000010738	ENSOARP00000006891	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.635
IGF1R	W5P0G0_SHEEP	ENSOARP00000010738	ENSOARP00000003908	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.966
INSR	IGF1R	ENSOARP00000000278	ENSOARP00000010738	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.861
INSR	INSRR	ENSOARP00000000278	ENSOARP00000006891	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.800
INSR	SLC2A4	ENSOARP00000000278	ENSOARP00000012275	Tyrosine-protein kinase receptor.	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.699
INSR	W5P0G0_SHEEP	ENSOARP00000000278	ENSOARP00000003908	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.996
INSRR	IGF1R	ENSOARP00000006891	ENSOARP00000010738	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.635
INSRR	INSR	ENSOARP00000006891	ENSOARP00000000278	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.800