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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASXL1ASXL transcriptional regulator 1. (1350 aa)    
Predicted Functional Partners:
W5NUE0_SHEEP
Ubiquitin carboxyl-terminal hydrolase.
    
 0.878
BAP1
Ubiquitin carboxyl-terminal hydrolase.
    
 0.878
FOXK1
Forkhead box K1.
   
 0.797
SETBP1
SET binding protein 1.
    
 0.732
TET2
Tet methylcytosine dioxygenase 2.
      
 0.716
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
   
 
 0.713
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 
 0.710
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase.
    
 0.696
ZRSR2
Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2.
    
 
 0.683
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
    
 0.681
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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