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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOLH1Folate hydrolase 1. (751 aa)    
Predicted Functional Partners:
ASPA
Aspartoacylase.
   
 
 0.929
RIMKLA
Ribosomal modification protein rimK like family member A.
     
 0.907
NAT8L
N-acetyltransferase domain-containing protein.
     
 0.904
RIMKLB
Ribosomal modification protein rimK like family member B.
     
 0.903
LENG1
Leukocyte receptor cluster member 1.
      
 0.785
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2.
  
  
0.781
SCN7A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
 0.758
RFX8
RFX family member 8, lacking RFX DNA binding domain.
      
 0.753
ZMYM3
Zinc finger MYM-type containing 3.
    
 0.729
DOCK4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
     
 0.669
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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