STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK1Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. (79 aa)    
Predicted Functional Partners:
LOC101112559
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.891
LOC101111795
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.878
W5Q219_SHEEP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.858
CTRC
Chymotrypsin C; Belongs to the peptidase S1 family.
   
 0.788
MSMB
Beta-microseminoprotein.
   
  
 0.734
WFDC3
Uncharacterized protein.
      
 0.704
LOC101116249
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.688
W5P9F4_SHEEP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.688
ACPP
Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family.
      
 0.640
SPINK9
Kazal-like domain-containing protein.
      
 0.613
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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