STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5P125_SHEEPUncharacterized protein. (111 aa)    
Predicted Functional Partners:
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.898
ATXN7L1
Ataxin 7 like 1.
 
      0.871
TAF10
TATA-box binding protein associated factor 10.
    
 0.864
TAF9B
TATA-box binding protein associated factor 9b.
    
 0.864
TADA3
Transcriptional adaptor 3.
    
 0.839
TAF12
TATA-box binding protein associated factor 12.
   
 0.832
SGF29
SAGA complex associated factor 29.
    
 0.830
SUPT3H
SPT3 homolog, SAGA and STAGA complex component.
    
 0.805
TAF6
TATA-box binding protein associated factor 6.
   
 0.801
ATXN7L3
Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]
    
 0.765
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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