STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1079 aa)    
Predicted Functional Partners:
ROBO1
Uncharacterized protein.
    
 0.959
CDC42
Cell division cycle 42.
   
 0.957
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3.
  
 
 
0.917
SRGAP2
Uncharacterized protein.
  
  
 
0.901
ITSN2
Intersectin 2.
   
0.843
CTU2
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family.
    
 
 0.826
CCDC102A
Coiled-coil domain containing 102A.
      
 0.815
SLTM
SAFB like transcription modulator.
     
 0.775
HEG1
Heart development protein with EGF like domains 1.
    
 0.739
QSER1
Glutamine and serine rich 1.
      
 0.724
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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