STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK18Protein kinase domain-containing protein. (254 aa)    
Predicted Functional Partners:
W5Q6X5_SHEEP
Protein kinase domain-containing protein.
 
      0.833
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.731
ORC2
Origin recognition complex subunit 2.
   
 0.699
CDC23
Cell division cycle 23.
    
 0.664
CCNJ
Cyclin J; Belongs to the cyclin family.
   
 0.660
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.657
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.657
CDKN1A
Uncharacterized protein.
   
 0.656
ANAPC1
Anaphase promoting complex subunit 1.
    
 0.648
CDK5R1
Cyclin dependent kinase 5 regulatory subunit 1.
    
 
 0.641
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.