STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO5F-box protein 5. (413 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.989
CDC20B
Cell division cycle 20B.
   
 0.973
CUL1
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.966
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
   
 
 0.952
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.952
FZR1
WD_REPEATS_REGION domain-containing protein.
   
 0.947
FBXW11
F-box and WD repeat domain containing 11.
    
 0.939
W5PNI9_SHEEP
WD_REPEATS_REGION domain-containing protein.
   
 0.933
RBX1
Ring-box 1.
     
 0.927
PLK1
Serine/threonine-protein kinase PLK.
   
 0.916
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.