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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC23IPSEC23 interacting protein. (1026 aa)    
Predicted Functional Partners:
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.987
SEC24A
SEC24 homolog A, COPII coat complex component.
   
 
 0.961
SEC31A
SEC31 homolog A, COPII coat complex component.
    
 0.950
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 
 0.942
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.907
SEC24B
SEC24 homolog B, COPII coat complex component.
   
 
 0.891
COPZ1
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
      
 0.869
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
     
 0.865
GALNT5
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.864
SEC24D
SEC24 homolog D, COPII coat complex component.
   
 
 0.863
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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