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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROGDIRogdi atypical leucine zipper. (350 aa)    
Predicted Functional Partners:
DMXL1
Dmx like 1.
    
 
 0.831
DMXL2
Dmx like 2.
    
 
 0.831
SMYD4
SET and MYND domain containing 4.
      
 0.803
LANCL1
LanC like 1.
      
 0.726
COPS7A
COP9 signalosome subunit 7A.
      
 0.705
PRPF31
Pre-mRNA processing factor 31.
      
 0.613
DHRS3
Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.613
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
      
 0.612
ATP6V1B2
Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.
   
 
 0.611
ATP6V1B1
Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.
   
 
 0.611
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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