STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF408Zinc finger protein 408. (634 aa)    
Predicted Functional Partners:
GPATCH3
G-patch domain containing 3.
   
    0.905
SAMD11
Sterile alpha motif domain containing 11.
    
 
 0.839
NDP
Norrin cystine knot growth factor NDP.
    
 
 0.691
TSPAN12
Tetraspanin.
      
 0.690
GRAMD4
GRAM domain containing 4.
    
 0.634
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
    
 
 0.632
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.624
BTBD9
BTB domain containing 9.
      
 0.614
GP9
Uncharacterized protein.
    
 
 0.606
ABHD12
Abhydrolase domain containing 12.
    
 
 0.591
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.