STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVL1Dishevelled segment polarity protein 1. (693 aa)    
Predicted Functional Partners:
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.
    
 0.937
VANGL2
Vang-like protein.
    
 0.925
VANGL1
Vang-like protein.
    
 0.923
AXIN1
Axin 1.
   
 0.918
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.902
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
    
 0.900
PRICKLE4
LIM zinc-binding domain-containing protein.
    
 0.883
PRICKLE3
Prickle planar cell polarity protein 3.
    
 0.882
CTNNB1
Catenin beta 1.
   
 0.872
KLHL12
Kelch like family member 12.
    
 0.871
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.