Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DVL1Dishevelled segment polarity protein 1. (693 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
   
 0.996
VANGL2
Vang-like protein.
    
 0.992
VANGL1
Vang-like protein.
    
 0.992
DVL2
Dishevelled segment polarity protein 2.
  
0.989
DVL3
Dishevelled segment polarity protein 3.
  
0.989
APC
APC regulator of WNT signaling pathway.
    
 0.988
PRICKLE3
Prickle planar cell polarity protein 3.
    
 0.985
PRICKLE4
LIM zinc-binding domain-containing protein.
    
 0.984
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.983
DAAM1
Dishevelled associated activator of morphogenesis 1.
    
 0.983
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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