STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB38RAB38, member RAS oncogene family. (233 aa)    
Predicted Functional Partners:
TYRP1
Uncharacterized protein.
   
  
 0.927
TYR
Uncharacterized protein.
   
  
 0.827
VAMP7
Uncharacterized protein; Belongs to the synaptobrevin family.
    
 
 0.812
HPS3
Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.
      
 0.779
HPS1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.
     
 0.728
ANKRD27
Ankyrin repeat domain 27.
    
 
 0.689
OCA2
OCA2 melanosomal transmembrane protein.
      
 0.680
GDI1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
    
 0.648
KBTBD8
Kelch repeat and BTB domain containing 8.
      
 0.644
HPS4
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.
     
 0.638
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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