STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URI1URI1 prefoldin like chaperone. (526 aa)    
Predicted Functional Partners:
POLR2E
RNA polymerase II subunit E.
    
 0.898
PIH1D1
PIH1 domain containing 1.
    
 0.898
RPAP3
RNA polymerase II associated protein 3.
    
 0.897
PFDN6
Prefoldin subunit 6.
    
 0.859
UXT
Ubiquitously expressed prefoldin like chaperone.
    
 0.853
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.845
RUVBL2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.790
BRINP1
BMP/retinoic acid inducible neural specific 1.
      
 0.781
FAM160A1
Family with sequence similarity 160 member A1.
   
  
 0.779
PFDN2
Uncharacterized protein.
    
 0.778
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.