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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BNIP1BCL2 interacting protein 1. (230 aa)    
Predicted Functional Partners:
USE1
Unconventional SNARE in the ER 1.
    
 0.997
STX18
Syntaxin 18.
   
 0.995
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
 0.990
RINT1
RAD50 interactor 1.
    
 0.986
SEC22C
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.840
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.840
NAPB
NSF attachment protein beta.
    
 0.778
NAPA
NSF attachment protein alpha.
    
 0.778
ZW10
Zw10 kinetochore protein.
    
 0.770
NBAS
Neuroblastoma amplified sequence.
   
 0.758
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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