STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB24RAB24, member RAS oncogene family. (205 aa)    
Predicted Functional Partners:
RABGEF1
Uncharacterized protein.
   
 0.975
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.904
RABL3
RAB, member of RAS oncogene family like 3.
   
  
 0.833
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.824
RAB3IP
Sec2p domain-containing protein.
      
 0.813
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.809
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.809
KCNJ10
Potassium voltage-gated channel subfamily J member 10.
      
 0.746
GRM1
Glutamate metabotropic receptor 1.
      
 0.738
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
      
 0.736
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.