STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDRGK1DDRGK domain containing 1. (323 aa)    
Predicted Functional Partners:
UFL1
UFM1 specific ligase 1.
    
 
 0.975
CDK5RAP3
CDK5 regulatory subunit associated protein 3.
    
 
 0.922
UFM1
Ubiquitin fold modifier 1.
    
 
 0.843
PCDHA2
Protocadherin alpha 2.
      
 0.824
PCDHA11
Protocadherin alpha 11.
      
 0.824
SRPRB
SRP receptor subunit beta.
    
 
 0.806
SPRY3
Sprouty RTK signaling antagonist 3.
      
 0.770
SYVN1
Synoviolin 1.
      
 0.719
SRP68
Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.
    
 
 0.715
SRP72
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
      
 0.686
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.