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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAGLNTransgelin; Belongs to the calponin family. (225 aa)    
Predicted Functional Partners:
ACTA2
Actin alpha 2, smooth muscle.
   
 0.784
W5PTX8_SHEEP
WD_REPEATS_REGION domain-containing protein.
    
 
 0.748
WDR90
Uncharacterized protein.
    
 
 0.748
MYL9
Myosin light chain 9.
   
 0.723
CNN1
Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
  
 
0.706
ACTG2
Actin gamma 2, smooth muscle.
   
 0.616
DSTN
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 
 0.606
ACTR1A
Actin related protein 1A.
   
 0.571
LMOD1
Uncharacterized protein.
   
  
 0.565
ENKUR
Enkurin, TRPC channel interacting protein.
   
 
 0.550
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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