STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD27Ankyrin repeat domain 27. (1048 aa)    
Predicted Functional Partners:
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.973
VAMP7
Uncharacterized protein; Belongs to the synaptobrevin family.
    
 0.886
LYZL6
Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family.
    
 0.847
RAB32
RAB32, member RAS oncogene family.
    
 
 0.841
AKAP7
A-kinase anchoring protein 7.
    
 
 0.750
RABEP2
Rabaptin, RAB GTPase binding effector protein 2.
   
 0.749
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
   
 0.749
RAB21
Uncharacterized protein.
   
 0.733
AP3D1
Adaptor related protein complex 3 subunit delta 1.
    
 0.706
RAB38
RAB38, member RAS oncogene family.
    
 
 0.689
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.