TCIM protein (Ovis aries) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TCIM

Transcriptional and immune response regulator. (124 aa)

Predicted Functional Partners:

ZC3H12A

0.735

RND1

0.672

GNAO1

0.622

GNG8

0.613

CPZ

0.587

GRHL3

0.586

SLC9A3

0.585

MAP3K7

0.545

EPGN

0.537

ARL14

0.534

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL14	TCIM	ENSOARP00000016067	ENSOARP00000004498	ADP ribosylation factor like GTPase 14; Belongs to the small GTPase superfamily. Arf family.	Transcriptional and immune response regulator.	0.534
CPZ	TCIM	ENSOARP00000014143	ENSOARP00000004498	Carboxypeptidase Z.	Transcriptional and immune response regulator.	0.587
EPGN	GNG8	ENSOARP00000016031	ENSOARP00000011424	Epithelial mitogen.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.420
EPGN	TCIM	ENSOARP00000016031	ENSOARP00000004498	Epithelial mitogen.	Transcriptional and immune response regulator.	0.537
GNAO1	GNG8	ENSOARP00000019903	ENSOARP00000011424	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.764
GNAO1	TCIM	ENSOARP00000019903	ENSOARP00000004498	G protein subunit alpha o1.	Transcriptional and immune response regulator.	0.622
GNG8	EPGN	ENSOARP00000011424	ENSOARP00000016031	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Epithelial mitogen.	0.420
GNG8	GNAO1	ENSOARP00000011424	ENSOARP00000019903	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit alpha o1.	0.764
GNG8	TCIM	ENSOARP00000011424	ENSOARP00000004498	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Transcriptional and immune response regulator.	0.613
GRHL3	TCIM	ENSOARP00000007111	ENSOARP00000004498	Grainyhead like transcription factor 3.	Transcriptional and immune response regulator.	0.586
MAP3K7	TCIM	ENSOARP00000013207	ENSOARP00000004498	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	Transcriptional and immune response regulator.	0.545
RND1	TCIM	ENSOARP00000020511	ENSOARP00000004498	Rho family GTPase 1.	Transcriptional and immune response regulator.	0.672
RND1	ZC3H12A	ENSOARP00000020511	ENSOARP00000021222	Rho family GTPase 1.	Zinc finger CCCH-type containing 12A.	0.675
SLC9A3	TCIM	ENSOARP00000017034	ENSOARP00000004498	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	Transcriptional and immune response regulator.	0.585
TCIM	ARL14	ENSOARP00000004498	ENSOARP00000016067	Transcriptional and immune response regulator.	ADP ribosylation factor like GTPase 14; Belongs to the small GTPase superfamily. Arf family.	0.534
TCIM	CPZ	ENSOARP00000004498	ENSOARP00000014143	Transcriptional and immune response regulator.	Carboxypeptidase Z.	0.587
TCIM	EPGN	ENSOARP00000004498	ENSOARP00000016031	Transcriptional and immune response regulator.	Epithelial mitogen.	0.537
TCIM	GNAO1	ENSOARP00000004498	ENSOARP00000019903	Transcriptional and immune response regulator.	G protein subunit alpha o1.	0.622
TCIM	GNG8	ENSOARP00000004498	ENSOARP00000011424	Transcriptional and immune response regulator.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.613
TCIM	GRHL3	ENSOARP00000004498	ENSOARP00000007111	Transcriptional and immune response regulator.	Grainyhead like transcription factor 3.	0.586