STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC6Coiled-coil domain containing 6. (374 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
     
 0.960
NCOA4
Uncharacterized protein.
     
 0.945
PDXDC1
Pyridoxal dependent decarboxylase domain containing 1.
      
 0.855
SRRM2
Serine/arginine repetitive matrix 2.
      
 0.812
CCDC120
Coiled-coil domain containing 120.
      
 0.707
CCDC68
Coiled-coil domain containing 68.
      
 0.694
THRAP3
Thyroid hormone receptor associated protein 3.
      
 0.692
CARHSP1
Calcium regulated heat stable protein 1.
      
 0.654
LSR
Lipolysis stimulated lipoprotein receptor.
      
 0.653
EPB41L2
Erythrocyte membrane protein band 4.1 like 2.
      
 0.619
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.