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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLCD3BTLC domain containing 3B. (237 aa)    
Predicted Functional Partners:
TCEA2
Transcription elongation factor A2.
      
 0.824
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.785
ARHGEF37
Rho guanine nucleotide exchange factor 37.
      
 0.772
FGD3
FYVE, RhoGEF and PH domain containing 3.
      
 0.747
EHBP1
EH domain binding protein 1.
      
 0.741
SNX24
Sorting nexin 24.
      
 0.701
ABHD12
Abhydrolase domain containing 12.
   
  
 0.694
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
  
 0.658
CDH20
Cadherin 20.
      
 0.654
SKOR1
SKI family transcriptional corepressor 1.
      
 0.614
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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