STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)    
Predicted Functional Partners:
GRHL1
Grainyhead like transcription factor 1.
   
  
 0.668
DIABLO
Uncharacterized protein.
      
 0.654
NAGK
N-acetylglucosamine kinase.
      
 0.614
NEK5
NIMA related kinase 5.
      
 0.613
RAB29
RAB29, member RAS oncogene family.
 
 
  
 0.591
PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
  
 0.581
ZNF593
Zinc finger protein 593.
      
 0.578
APBB3
Amyloid beta precursor protein binding family B member 3.
   
  
 0.537
RIOK2
RIO kinase 2.
      
 0.535
NOP16
Uncharacterized protein.
      
 0.534
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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