CLRN1 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CLRN1

Clarin 1. (232 aa)

Predicted Functional Partners:

USH1C

0.785

USH1G

0.772

CIB2

0.737

WHRN

0.697

DCC

0.691

CDH23

0.677

USH2A

0.661

PCDH15

0.621

PDZD7

0.621

MYO7A

0.614

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH23	CIB2	ENSOARP00000007171	ENSOARP00000000542	Cadherin related 23.	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	0.707
CDH23	CLRN1	ENSOARP00000007171	ENSOARP00000004574	Cadherin related 23.	Clarin 1.	0.677
CDH23	MYO7A	ENSOARP00000007171	ENSOARP00000014603	Cadherin related 23.	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.960
CDH23	PCDH15	ENSOARP00000007171	ENSOARP00000014166	Cadherin related 23.	Protocadherin related 15.	0.995
CDH23	PDZD7	ENSOARP00000007171	ENSOARP00000017335	Cadherin related 23.	PDZ domain containing 7.	0.597
CDH23	USH1C	ENSOARP00000007171	ENSOARP00000003349	Cadherin related 23.	USH1 protein network component harmonin.	0.973
CDH23	USH1G	ENSOARP00000007171	ENSOARP00000012686	Cadherin related 23.	USH1 protein network component sans.	0.822
CDH23	USH2A	ENSOARP00000007171	ENSOARP00000011524	Cadherin related 23.	Usherin.	0.834
CDH23	WHRN	ENSOARP00000007171	ENSOARP00000006437	Cadherin related 23.	Whirlin.	0.700
CIB2	CDH23	ENSOARP00000000542	ENSOARP00000007171	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Cadherin related 23.	0.707
CIB2	CLRN1	ENSOARP00000000542	ENSOARP00000004574	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Clarin 1.	0.737
CIB2	MYO7A	ENSOARP00000000542	ENSOARP00000014603	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.723
CIB2	PCDH15	ENSOARP00000000542	ENSOARP00000014166	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Protocadherin related 15.	0.681
CIB2	PDZD7	ENSOARP00000000542	ENSOARP00000017335	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	PDZ domain containing 7.	0.634
CIB2	USH1C	ENSOARP00000000542	ENSOARP00000003349	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	USH1 protein network component harmonin.	0.742
CIB2	USH1G	ENSOARP00000000542	ENSOARP00000012686	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	USH1 protein network component sans.	0.817
CIB2	USH2A	ENSOARP00000000542	ENSOARP00000011524	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Usherin.	0.678
CIB2	WHRN	ENSOARP00000000542	ENSOARP00000006437	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	Whirlin.	0.719
CLRN1	CDH23	ENSOARP00000004574	ENSOARP00000007171	Clarin 1.	Cadherin related 23.	0.677
CLRN1	CIB2	ENSOARP00000004574	ENSOARP00000000542	Clarin 1.	Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release. May be involved in the mechanotransduction process.	0.737