STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPAZ1Protein TOPAZ1; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear. (1639 aa)    
Predicted Functional Partners:
TCTE3
T-complex-associated-testis-expressed 3.
      
 0.890
FATE1
Miff domain-containing protein.
      
 0.835
APBA1
Amyloid beta precursor protein binding family A member 1.
      
 0.834
MTURN
Maturin, neural progenitor differentiation regulator homolog.
      
 0.823
PCDHA5
Protocadherin alpha 5.
      
 0.823
BABAM1
BRISC and BRCA1 A complex member 1.
      
 0.747
KCNH6
Potassium voltage-gated channel subfamily H member 6.
   
  
 0.742
PPP1R18
Protein phosphatase 1 regulatory subunit 18.
      
 0.728
TUBGCP5
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
 0.705
CWC25
CWC25 spliceosome associated protein homolog.
   
  
 0.695
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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