STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5P2F2_SHEEPIRS-type PTB domain-containing protein. (270 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.730
CSK
Tyrosine-protein kinase.
   
 0.678
W5QAJ7_SHEEP
Uncharacterized protein.
    
 0.644
CBL
Cbl proto-oncogene.
    
 0.621
SMIM1
Small integral membrane protein 1 (Vel blood group).
      
 0.613
TBC1D10C
TBC1 domain family member 10C.
   
  
 0.598
BTK
Tyrosine-protein kinase.
   
 0.595
GAB1
GRB2 associated binding protein 1.
    
 0.577
EMB
Embigin.
      
 0.534
RANBP17
RAN binding protein 17.
      
 0.532
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.