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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOD1-2Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (152 aa)    
Predicted Functional Partners:
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.979
PPARGC1A
PPARG coactivator 1 alpha.
     
 0.945
CCS
Copper chaperone for superoxide dismutase.
  
0.941
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.937
VDAC1
Uncharacterized protein.
   
 
 0.935
PPP3R1
Uncharacterized protein.
    
 0.926
PARK7
Parkinsonism associated deglycase.
  
 0.920
TOMM40
Translocase of outer mitochondrial membrane 40.
     
 0.915
NEFL
Neurofilament light; Belongs to the intermediate filament family.
     
 0.914
C9orf72
C9orf72-SMCR8 complex subunit.
      
 0.911
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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