STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK1Cell division cycle 2 protein isoform 1; Belongs to the protein kinase superfamily. (297 aa)    
Predicted Functional Partners:
W5P6X3_SHEEP
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.999
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.999
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.999
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.998
WEE1
Wee1-like protein kinase.
   
 0.995
PLK1
Serine/threonine-protein kinase PLK.
   
0.995
CDC25A
Cell division cycle 25A.
   
 0.994
CDC25C
Cell division cycle 25C.
   
 0.991
CDC25B
Cell division cycle 25B.
   
 0.986
W5PTP9_SHEEP
Uncharacterized protein; Belongs to the cyclin family.
   
 0.982
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.