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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERAC1Serine active site containing 1. (654 aa)    
Predicted Functional Partners:
TMEM242
Transmembrane protein 242.
      
 0.833
SCAF8
SR-related CTD associated factor 8.
      
 0.818
TULP4
TUB like protein 4.
      
 0.769
TFB1M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
  
 0.702
GTF2H5
General transcription factor IIH subunit 5.
      
 0.613
ABITRAM
Actin binding transcription modulator.
      
 0.612
HSDL1
Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.612
SPRYD7
SPRY domain containing 7.
      
 0.592
NIPAL3
NIPA like domain containing 3.
      
 0.589
PDZD3
PDZ domain containing 3.
      
 0.583
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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