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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5P2K5_SHEEPIF rod domain-containing protein; Belongs to the intermediate filament family. (396 aa)    
Predicted Functional Partners:
KRT8
Keratin 8; Belongs to the intermediate filament family.
   
0.959
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.697
ALAS1
5'-aminolevulinate synthase 1.
      
 0.569
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
      
 0.525
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.464
RANBP2
RAN binding protein 2.
   
 0.454
EPCAM
Thyroglobulin type-1 domain-containing protein.
   
  
 0.451
KRT82
Keratin 82; Belongs to the intermediate filament family.
   
0.421
RPA2
Replication protein A2.
      
 0.402
W5Q429_SHEEP
Uncharacterized protein.
   
 0.401
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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