node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CACYBP | SIAH1 | ENSOARP00000014671 | ENSOARP00000018181 | Calcyclin binding protein. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.996 |
CACYBP | SIAH2 | ENSOARP00000014671 | ENSOARP00000004657 | Calcyclin binding protein. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.755 |
CACYBP | UBE2V2 | ENSOARP00000014671 | ENSOARP00000013810 | Calcyclin binding protein. | Ubiquitin conjugating enzyme E2 V2. | 0.443 |
FPGT | LRRIQ3 | ENSOARP00000013106 | ENSOARP00000013088 | Fucose-1-phosphate guanylyltransferase. | Leucine rich repeats and IQ motif containing 3. | 0.871 |
FPGT | SIAH2 | ENSOARP00000013106 | ENSOARP00000004657 | Fucose-1-phosphate guanylyltransferase. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.674 |
HIPK2 | SIAH1 | ENSOARP00000012589 | ENSOARP00000018181 | Homeodomain interacting protein kinase 2. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.757 |
HIPK2 | SIAH2 | ENSOARP00000012589 | ENSOARP00000004657 | Homeodomain interacting protein kinase 2. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.635 |
LATS2 | SIAH2 | ENSOARP00000014720 | ENSOARP00000004657 | Large tumor suppressor kinase 2. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.814 |
LRRIQ3 | FPGT | ENSOARP00000013088 | ENSOARP00000013106 | Leucine rich repeats and IQ motif containing 3. | Fucose-1-phosphate guanylyltransferase. | 0.871 |
LRRIQ3 | SIAH2 | ENSOARP00000013088 | ENSOARP00000004657 | Leucine rich repeats and IQ motif containing 3. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.784 |
SIAH1 | CACYBP | ENSOARP00000018181 | ENSOARP00000014671 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Calcyclin binding protein. | 0.996 |
SIAH1 | HIPK2 | ENSOARP00000018181 | ENSOARP00000012589 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Homeodomain interacting protein kinase 2. | 0.757 |
SIAH1 | SIAH2 | ENSOARP00000018181 | ENSOARP00000004657 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.795 |
SIAH1 | SNCA | ENSOARP00000018181 | ENSOARP00000019872 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Gamma-synuclein; Belongs to the synuclein family. | 0.765 |
SIAH1 | UBE2V2 | ENSOARP00000018181 | ENSOARP00000013810 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Ubiquitin conjugating enzyme E2 V2. | 0.726 |
SIAH1 | USP13 | ENSOARP00000018181 | ENSOARP00000022236 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.580 |
SIAH1 | USP19 | ENSOARP00000018181 | ENSOARP00000016018 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Ubiquitin specific peptidase 19. | 0.791 |
SIAH2 | CACYBP | ENSOARP00000004657 | ENSOARP00000014671 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Calcyclin binding protein. | 0.755 |
SIAH2 | FPGT | ENSOARP00000004657 | ENSOARP00000013106 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Fucose-1-phosphate guanylyltransferase. | 0.674 |
SIAH2 | HIPK2 | ENSOARP00000004657 | ENSOARP00000012589 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Homeodomain interacting protein kinase 2. | 0.635 |