STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEURL1Neuralized E3 ubiquitin protein ligase 1. (556 aa)    
Predicted Functional Partners:
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.712
AGTPBP1
ATP/GTP binding protein 1.
    
 
 0.664
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
   
  
 0.618
DNAJB14
DnaJ heat shock protein family (Hsp40) member B14.
    
 
 0.612
PRUNE2
Prune homolog 2 with BCH domain.
      
 0.608
HIVEP2
Human immunodeficiency virus type I enhancer binding protein 2.
      
 0.579
ADCY1
Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
  
 0.542
PAK6
Non-specific serine/threonine protein kinase.
   
  
 0.542
FAT3
FAT atypical cadherin 3.
      
 0.539
CHRNG
Cholinergic receptor nicotinic gamma subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.534
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.