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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (488 aa)    
Predicted Functional Partners:
C1S
Complement C1s; Belongs to the peptidase S1 family.
  
0.964
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.772
CLSTN3
Calsyntenin 3.
     
 0.730
SFTPD
C-type lectin domain-containing protein.
   
 0.635
CALHM2
Calcium homeostasis modulator family member 2.
   
  
 0.539
C1QA
Complement C1q A chain.
   
 0.531
LOXL4
Lysyl oxidase like 4.
    
 0.527
RHPN2
Rhophilin Rho GTPase binding protein 2.
      
 0.521
TLL1
Metalloendopeptidase.
    
 0.516
SLC14A1
Urea transporter 1; Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across [...]
      
 0.499
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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