STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP3LDL receptor related protein 3. (585 aa)    
Predicted Functional Partners:
CNST
Consortin, connexin sorting protein.
      
 0.893
VWA5B2
Von Willebrand factor A domain containing 5B2.
      
 0.689
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.630
ITSN2
Intersectin 2.
    
 0.613
ARHGEF39
Rho guanine nucleotide exchange factor 39.
   
  
 0.593
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.587
STAB1
FAS1 domain-containing protein.
    
 0.570
GSK3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.526
ARHGEF37
Rho guanine nucleotide exchange factor 37.
   
  
 0.485
EGFR
Receptor protein-tyrosine kinase.
   
 0.481
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.