GNA12 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GNA12

G protein subunit alpha 12. (383 aa)

Predicted Functional Partners:

ARHGEF12

0.992

GNA13

0.987

ARHGEF11

0.980

S1PR2

0.968

ADRA1D

0.962

LPAR1

0.961

ADRA1B

0.959

GNG12

0.959

ADRA1A

0.954

S1PR3

0.951

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	ADRA1B	ENSOARP00000010454	ENSOARP00000011068	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1B.	0.940
ADRA1A	ADRA1D	ENSOARP00000010454	ENSOARP00000000238	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1D.	0.933
ADRA1A	ARHGEF11	ENSOARP00000010454	ENSOARP00000007160	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 11.	0.409
ADRA1A	ARHGEF12	ENSOARP00000010454	ENSOARP00000018652	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 12.	0.485
ADRA1A	GNA12	ENSOARP00000010454	ENSOARP00000004746	Adrenoceptor alpha 1A.	G protein subunit alpha 12.	0.954
ADRA1A	GNA13	ENSOARP00000010454	ENSOARP00000016438	Adrenoceptor alpha 1A.	G protein subunit alpha 13.	0.963
ADRA1A	GNG12	ENSOARP00000010454	ENSOARP00000012180	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.420
ADRA1B	ADRA1A	ENSOARP00000011068	ENSOARP00000010454	Adrenoceptor alpha 1B.	Adrenoceptor alpha 1A.	0.940
ADRA1B	ADRA1D	ENSOARP00000011068	ENSOARP00000000238	Adrenoceptor alpha 1B.	Adrenoceptor alpha 1D.	0.979
ADRA1B	ARHGEF12	ENSOARP00000011068	ENSOARP00000018652	Adrenoceptor alpha 1B.	Rho guanine nucleotide exchange factor 12.	0.532
ADRA1B	GNA12	ENSOARP00000011068	ENSOARP00000004746	Adrenoceptor alpha 1B.	G protein subunit alpha 12.	0.959
ADRA1B	GNA13	ENSOARP00000011068	ENSOARP00000016438	Adrenoceptor alpha 1B.	G protein subunit alpha 13.	0.960
ADRA1B	GNG12	ENSOARP00000011068	ENSOARP00000012180	Adrenoceptor alpha 1B.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.431
ADRA1D	ADRA1A	ENSOARP00000000238	ENSOARP00000010454	Adrenoceptor alpha 1D.	Adrenoceptor alpha 1A.	0.933
ADRA1D	ADRA1B	ENSOARP00000000238	ENSOARP00000011068	Adrenoceptor alpha 1D.	Adrenoceptor alpha 1B.	0.979
ADRA1D	ARHGEF12	ENSOARP00000000238	ENSOARP00000018652	Adrenoceptor alpha 1D.	Rho guanine nucleotide exchange factor 12.	0.580
ADRA1D	GNA12	ENSOARP00000000238	ENSOARP00000004746	Adrenoceptor alpha 1D.	G protein subunit alpha 12.	0.962
ADRA1D	GNA13	ENSOARP00000000238	ENSOARP00000016438	Adrenoceptor alpha 1D.	G protein subunit alpha 13.	0.962
ADRA1D	GNG12	ENSOARP00000000238	ENSOARP00000012180	Adrenoceptor alpha 1D.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.431
ARHGEF11	ADRA1A	ENSOARP00000007160	ENSOARP00000010454	Rho guanine nucleotide exchange factor 11.	Adrenoceptor alpha 1A.	0.409