STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK4Mitogen-activated protein kinase 4. (583 aa)    
Predicted Functional Partners:
MAPK6
Mitogen-activated protein kinase 6.
  
 
0.909
XPO1
Exportin 1.
    
 0.854
MAPKAPK5
MAPK activated protein kinase 5.
   
0.760
CCDC68
Coiled-coil domain containing 68.
      
 0.690
NCOA3
Nuclear receptor coactivator.
    
 0.653
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
  
0.638
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
0.634
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
0.633
MAP2K3
Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
  
0.631
MAP2K2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
0.629
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (18%) [HD]