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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK7Serine peptidase inhibitor, Kazal type 7 (putative). (85 aa)    
Predicted Functional Partners:
CSRNP3
Cysteine and serine rich nuclear protein 3.
      
 0.662
EAF2
ELL associated factor 2.
      
 0.660
HMCN2
Hemicentin 2.
      
 0.646
NXNL2
Nucleoredoxin like 2.
      
 0.612
SLITRK4
SLIT and NTRK like family member 4.
      
 0.594
LAMB2
Laminin subunit beta 2.
      
 0.592
ATP6V1G1
V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.587
TREM1
Triggering receptor expressed on myeloid cells 1.
      
 0.574
MSS51
MSS51 mitochondrial translational activator.
      
 0.574
W5PNA3_SHEEP
Uncharacterized protein.
      
 0.574
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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