STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (762 aa)    
Predicted Functional Partners:
TMCC3
Transmembrane and coiled-coil domain family 3.
      
 0.852
PTPRQ
Protein tyrosine phosphatase receptor type Q.
    
 0.789
CHN2
Chimaerin; GTPase-activating protein for p21-rac.
      
 0.783
W5P6D4_SHEEP
Uncharacterized protein.
    
 0.777
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.776
INTS13
Integrator complex subunit 13.
   
 0.771
CLCA4
Chloride channel accessory 4.
    
 0.758
MANF
Mesencephalic astrocyte derived neurotrophic factor.
      
 0.744
INTS3
Integrator complex subunit 3.
    
 0.739
INTS5
Integrator complex subunit 5.
    
 0.739
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.