STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAC14VAC14 component of PIKFYVE complex. (752 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
    
 0.999
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
    
 0.996
DIPK2A
Divergent protein kinase domain 2A.
    
 0.918
CTC1
CST telomere replication complex component 1.
      
 0.823
STK40
Serine/threonine kinase 40.
   
 
 0.805
YARS1
Tyrosine--tRNA ligase.
      
 0.786
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
      
 0.769
KPNA6
Importin subunit alpha; Functions in nuclear protein import.
      
 0.753
USP33
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
  
 0.751
SOAT1
O-acyltransferase.
      
 0.727
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.